Cancer of The Uterus From Gross Appearances to Ultrastructure Second Edition【2025|PDF|Epub|mobi|kindle电子书版本百度云盘下载】

Cancer of The Uterus From Gross Appearances to Ultrastructure Second EditionPDF格式电子书版下载

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SECTION Ⅰ CANCER OF THE ECTOCERVIX3

1．DIAGNOSTIC METHODS5

Introduction5

Cytology7

Karyology11

Schiller Test12

Colposcopy12

Colpomicroscopy13

2．THE NORMAL AND PATHOLOGICAL APPEARANCES OF THE ECTOCERVIX GIVEN BY THE DIFFERENT METHODS16

Introduction16

Normal Pictures16

Nonmalignant Patterns23

Erosion and Ectropion23

Squamous Metaplasia26

Colpitis29

Vaginal Trichomoniasis31

Polyp35

The Ectocervix During the Menopause38

The Ectocervix During Pregnancy40

Vaginal Prolapse43

Precancerous and Cancerous Conditions44

Leukoplakia44

Base of Leukoplakia48

Mosaic Leukoplakia50

Papillary Base55

Erosio Vera (True Ulcer)58

Red Zone59

Iodine-negative，Sharply-demarcated Zones61

Carcinoma63

Remarks on Carcinoma In Situ70

Remarks on Invasive Carcinoma and Its Recurrences77

3．MORPHOLOGICAL DETERMINATION OF THE RADIOCURABILITY OF CARCINOMA OF THE ECTOCERVIX80

Introduction80

Radiation Lesions of the Various Tissues81

Radiation Lesions of the Chromosomes82

Radiation Cell Changes on the Cancerous and Normal Ectocervix86

Radiation Cell Changes on Endocervical Glandular Epithelium89

Lesions of the Bladder，Ovaries and Pelvic Lymph Nodes，caused by Radiotherapy of Carcinoma of the Ectocervix91

Tests of Radiocurability95

Changes Produced by High Voltage and Isotope Therapies102

4．HISTOCHEMICAL INVESTIGATIONS107

Introduction107

Carbohydrates107

Nucleic Acids112

Enzymes114

Amount of Beta-glucuronidase in the Vaginal Fluid116

Techniques120

5．HISTOPHYSICAL INVESTIGATIONS121

Introduction121

Histophotometric Technique121

Ultraviolet Spectrophotometry122

Ultraviolet Microspectrography123

Phase Contrast Microscopy124

Interference Microscopy126

Fluorescence Microscopy128

The Cytoanalyzer132

6．HORMONAL INVESTIGATIONS134

Introduction134

Estrogens134

Progesterone137

Androgens138

Cytological Determination of the Hormonal State With Particular Reference of Physiological，Radiation-induced and Surgical (by Oophorectomy，Adrenalectomy and Hypophysectomy) Menopause139

Cytohormonal Diagnosis of Ovarian Dysfunctions143

Modifications Induced by Hormones on the Vaginal Epithelium145

Correlations Between Vaginal Cytology and the Level of Urinary Estrogens148

7．CONSIDERATIONS ON ENDOCRINE SURGERY149

Introduction149

Ovario-adrenalectomy150

Surgical Hypophysectomy154

Isotopic Hypophysectomy156

Behavior of Urinary Steriods After Endocrine Surgery156

Persistence of Hormonal Activity After Endocrine Surgery158

SECTION Ⅱ CANCER OF THE ENDOCERVIX AND ENDOMETRIUM161

8．CANCER OF THE ENDOCERVIX163

Introduction163

Histology of the Endocervix163

The Cyclic Changes of the Cervical Mucus164

Cytology of the Cervical Canal165

Phase Contrast Microscopy of Endocervical Cells165

Non-neoplastic Pictures of the Endocervix166

Neoplastic Pictures of the Endocervix168

9．CANCER OF THE ENDOMETRIUM173

Introduction173

Histology of the Normal Endometrium174

Exfoliative Cytology of the Normal and Pathological Endometrium176

Phase Contrast Microscopy of the Endometrial Cells181

Histochemistry of the Normal and Abnormal Endometrium and of Adenocarcinoma of the Endometrium181

Non-neoplastic Histological Pictures of the Endometrium183

Histological Pattern of Carcinomatous Endometrium189

10．CYTOLOGIC DIAGNOSIS OF METASTASES FROM CARCINOMA OF THE ECTOCERVIX AND ENDOMETRIUM194

Introduction194

Pulmonary Cytodiagnosis194

Urologic Cytodiagnosis196

Cytology of Pleural and Peritoneal Effusions197

Detection of Neoplastic Cells in the Peripheral Blood200

SECTION Ⅲ ELECTRON MICROSCOPY ON CELLS OF THE PORTIO AND ENDOMETRIUM205

11．CELLULAR ULTRASTRUCTURE207

Introduction207

Cellular Ultrastructure and the Functional Significance of the Various Cell Constituents208

Differences Between Normal and Malignant Cells Under the Electron Microscopy220

Technique of Electron Microscopy223

12．ELECTRON MICROSCOPY ON CELLS OF THE ECTOCERVIX228

Introduction228

Normal Ectocervix228

Carcinoma of the Ectocervix233

Electron Microscopy of Carcinoma of the Ectocervix after Irradiation241

13．ELECTRON MICROSCOPY ON CELLS OF THE ENDOMETRIUM254

Introduction254

Normal Endometrium254

Carcinoma of the Endometrium256

Modifications Induced by Synthetic Progestogens on Endometrium257

Conclusions258

14．REMARKS ON ULTRASTRUCTURAL-BIOCHEMICAL CHANGES IN NEOPLASTIC CELLS AND THEIR IMPLICATIONS FOR CARCINOGENESIS，DIFFERENTIATED AND UNDIFFERENTIATED NEOPLASMS，AND VARIOUS DEGREES OF MORPHOLOGICAL ATYPIA IN NEOPLASTIC CELLS306

SECTION Ⅳ THE SENILE CERVIX AND ENDOMETRIUM EXAMINED WITH THE LIGHT AND ELECTRON MICROSCOPES309

15．THE SENILE CERVIX AND ENDOMETRIUM311

Introduction311

Light Microscope Examination of Senile Cells311

The Senile Ectocervix Examined by Means of the Electron Microscope314

The Senile Endometrium Examined by Means of the Electron Microscope321

The Nuclei of the Senile Ectocervix and Endometrium326

Discussion326

Conclusions and Prospects for Future Research in the Study of the Senile Cells．Role of Senility in the Carcinogenesis329

SECTION Ⅴ FINAL CONSIDERATIONS AND SYNOPSIS OF THE ORIGINAL CONTRIBUTIONS333

16．FINAL CONSIDERATIONS335

Synopsis of the Original Contributions341

BIBLIOGRAPHY344

Miscellanea344

Vaginal Cytology345

Colposcopy348

Pathology of the Ectocervix349

Pregnancy351

Radiation-induced Changes in Various Tissues352

Histochemistry353

Histophysics353

Hormonal Evaluation354

Endocrine Therapy of Cancer355

Pathology of the Endocervix356

Pathology of the Endometrium356

Cytodiagnosis of Metastases from Uterine Cancer and Detection of Tumoral Cells in Circulating Blood358

Functional Biochemistry of Cell Structures359

Electron Microscopy360

Senile Changes in Cells362

Authors Index365

Analytical Index369